What are the most important reactions in drug synthesis and stability?

This is a rough draft that I hope to flesh out based on feedback, i.e. "I'm asking, not telling". Please leave a comment or tweet me

Synthesis
1. Aromatic electrophilic substitution of heteroaromatics
2. Suzuki coupling of heteroaryl halides
3. Diels-Alder reaction (of what)?
4. Michael reaction (of what)?
5. Friedel-Crafts alkylation (of what)?
6. Nazarov cyclization reaction (of what)?
7. ...

Stability (Probably solvolysis and oxidative degradation, but can we be more specific)
1. Autooxidation of C-H bonds?
2. Ester hydrolysis?
3. ..



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